Plinestยฎ Classic is an advanced, CE-certified viscoelastic gel formulated for professional intradermal skin rejuvenation and tissue bio-regeneration. Developed by the pioneering Italian biopharmaceutical manufacturer Mastelli, this formulation utilizes patented PN-HPTยฎ (Polynucleotides High Purification Technology), a natural-origin polymer derived from controlled fish DNA sources intended for human consumption.
Unlike traditional dermal fillers that physically introduce artificial volume to the tissue, Plinestยฎ Classic operates on a cellular level. Once administered into the dermis, the highly purified polynucleotides support the extracellular matrix (ECM) by activating fibroblasts, enhancing protein production, and accelerating natural skin repair mechanisms. This trophic action promotes physiological tissue remodelling, helping to visibly restore skin rigidity, counter early laxity, and rebalance skin texture.
This product is intended strictly for use by registered aesthetic practitioners and healthcare professionals.
Key Specifications
- Manufacturer: Mastelli S.r.l. (Sanremo, Italy)
- Active Ingredient Concentration: 20 mg/ml (40 mg per syringe) of highly purified Polynucleotides (PN-HPTยฎ)
- Classification: Class III Medical Device
- Recommended Injection Depth: Intradermal (dermal layer)
- Viscoelasticity: Viscoelastic, non-pyrogenic intradermal gel
- Storage Requirements: Store between 2ยฐC and 25ยฐC away from direct heat
Primary Clinical Indications & Treatment Areas
Plinestยฎ Classic is indicated for preventative anti-ageing maintenance, the restoration of skin quality, and the correction of areas with high fibrous content. It is clinically evaluated to target:
- Facial Rejuvenation: Toning and improving overall structural elasticity across the malar and submalar zones.
- Neck & Dรฉcolletage: Revitalizing crepey, stressed, or thin skin affected by early laxity.
- Hands: Deeply hydrating and reinforcing skin firmness on the dorsal surface of the hands.
- Fibrous Tissue Remodelling: Smoothing and improving the appearance of deep, atrophic acne scars or stretch marks.
- Body Contouring Complement: Targeting restricted localized laxity on areas such as the inner arms, knees, or thighs.
Recommended Protocol
- Initial Course: 3 to 4 treatment sessions spaced 14 to 21 days apart, depending on baseline skin status.
- Administration Method: Micro-droplet (0.2 ml per point) or retrograde-linear techniques.
- Maintenance Phase: Single session every 1 to 3 months to preserve cellular bio-regeneration.
Box Contents
- Packaging Contents: 1 x 2ml pre-filled, sterile syringe
- Included Accessories: 2 x sterile 30G ยฝ needles
